Anti-RHOC 抗体说明书
Quantity size: 0.1ml (dilute with pH 7.4 0.01 M PBS or diluent of antibody)
Background: RHOC (ras homolog gene family, member C) is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. Also known as: RhoC protein; RHOC; ARH9; ARHC; ARH 9; H9; MGC1448; MGC61427; Oncogene RHO H9; Ras homolog gene family member C; RAS related homolog 9; RHOC; Rho related GTP binding protein RhoC; RhoC GTPase; RHOH 9; RHOH9; Small GTP binding protein RhoC.
Specificity: · anti-RHOC is a rabbit monoclonal antibody unconjugated
· specific for RHOC of human, mouse and rat
· broadly reactive with mammalian species
· epitope mapping in the middle of RHOC of human, mouse and rat
origin
·use for western blotting,elisa, immunoprecipitation
and immunohistochemistry
· affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt:21kDa
Application: ·Western blotting: 1:100-500
· Immunohistochemistry: 1:100-500
· ELISA: 1:500-1000
· Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Anti-RHOC 抗体说明书
